USP35 (Ubiquitin Specific Peptidase 35) Polyclonal
$543.00
USP35 is a member of the peptidase C19 family. USP35 is involved in various cellular processes, including cancer development and immune response. USP35 plays a role in regulating cell mitosis by deubiquitinating Aurora B and preventing its degradation. USP35 can also regulate MFN2 abundance and PARK2-mediated mitophagy. USP35 has 2 isoforms with the molecular mass of 84 and 113 kDa. USP35 is overexpressed in various cancers, including colorectal cancer, breast cancer, and lung cancer. USP35 is implicated in cancer by affecting cell proliferation, chemo-resistance, and immune evasion.
Clone
Polyclonal
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human, mouse
Cellular Localization
Cytoplasm, mitochondrion
Positive Control
Colon cancer, lung cancer, breast cancer
Applications
IHC, WB
Intended Use
Research Use Only