BRAF, a kinase-encoding gene from the RAS/RAF/MEK/ERK pathway, recently has being studied in all malignant melanomas, including thyroid cancer, malignant melanoma, ovarian cancer, colorectal cancer (1). The most common mutations in BRAF occur at the valine at residue 600 (V600) within exon 15, and may be a predictive biomarker for limited response to anti-EGFR therapy.
Cancer Type
Leukemia
Intended Use
Research Use Only.