Splicing factor 3b, subunit 1 is a gene that codes for part of the splicing factor 3b protein complex. The function of the complex is associated with transcription and mRNA processing. SF3B1 mutations are observed in MDS, chronic lymphocytic leukemia (CLL), AML, and chronic myelomonocytic leukemia (CMML), Solid tumors include uveal melanomas, pancreatic cancers and breast cancer.
Intended Use
Research Use Only.