Ultra-Sensitive K-Ras mutation detection kit_12,13,59,61,117,146

KRAS ((Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog) gene encodes a small GTPase protein that functions downstream of EGFR-induced cell signaling and participates in the activation of important oncogenic signaling pathways (1). Oncogenic KRAS gene mutations tend to cause constitutive activation, on which the tumor relies to maintain its growth, apoptosis, angiogenesis and metastasis. Therefore, certain studies have been focused on the relation of KRAS gene mutation on different cancer types and others.