Topoisomerase II alpha [TOP2A/1362]

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Topoisomerase IIα plays important roles in synthesis and transcription of DNA, as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topoisomerase IIα is also implicated in drug resistance of tumor cells

Catalog No. MC0246, MC0246RTU7

Clone
TOP2A/1362

Isotype
IgG2b/k

Host species
Mouse

Species Reactivity
Human

Cellular Localization
membrane

Positive Control
urinary bladder, urothelial carcinoma

Applications
ELISA, IHC

Intended Use
Research Use Only

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