Topoisomerase IIα plays important roles in synthesis and transcription of DNA, as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topoisomerase IIα is also implicated in drug resistance of tumor cells
Catalog No. MC0246, MC0246RTU7
Clone
TOP2A/1362
Isotype
IgG2b/k
Host species
Mouse
Species Reactivity
Human
Cellular Localization
membrane
Positive Control
urinary bladder, urothelial carcinoma
Applications
ELISA, IHC
Intended Use
Research Use Only