Spectrin (Erythrocyte Marker) [SPTA1/2939R]

Spectrin alpha chain, erythrocytic 1 (SPTA1) is a member of the family of alpha-spectrin proteins. It is primarily composed of 22 spectrin repeats, which are involved in dimer formation. Spectrin antibodies react with erythroid cells at all stages of maturation in the bone marrow. Spectrin is a useful target in identification of erythroid leukemias. It may be a superior marker to glycophorin for the identification of erythroid precursors in paraffin embedded sections.