Coronavirus is a genus of animal virus that belongs to the family Coronaviridae. Coronaviruses are enveloped viruses with a positive-sense single-stranded RNA genome and a helical symmetry that resemble a crown when viewed under an electron microscope. They primarily infect the upper respiratory and gastrointestinal tract of mammals and birds. Four or five different known strains of Coronavirus infect humans and are thought to be the cause of many common colds. The most publicized human Coronavirus, SARS-CoV, causes both upper and lower respiratory tract infections and can also cause gastroenteritis. This antibody also reacts with feline infectious peritonitis virus type 1 and 2 and is known to be specific for the nucleocapsid. It is also known to react with canine coronavirus (CCV), pig coronavirus transmissible gastroenteritis virus (TGEV) and ferret coronavirus. Some specific activity has been detected against bovine coronavirus (BCV). Clone FIPV3-70 exhibits negative reactivity against Feline Leukemia virus, Feline Immunodeficiency virus, Feline Calcvirus, Feline Herpes virus, Canine Adenovirus (type 2), Canine Distemper virus, Canine parvovirus and Canine Parainfluenza virus. It has been reported that clone FIPV3 recognizes the SARS-Cov-2 nucleocapsid protein.
Clone
FIPV3-70
Isotype
IgG2a
Host species
Mouse
Species Reactivity
SARS-CoV-2
Cellular Localization
Cytoplasm and the nucleolus, a subnuclear structure
Positive Control
SARS-CoV-2 infected lung tissue
Applications
Flow Cyt., ELISA, ICC/IF, IHC, WB
Intended Use
Research Use Only