NSE is specifically detected in neurons and neurodendocrine cells, and their corresponding tumors. Anti-NSE antibody is a useful marker for identification of peripheral nerves, neural and neuroendocrine tumors, such as neuroblastomas, retinoblastomas, desmoplastic melanoma, and small cell lung carcinoma when used with a panel of antibodies (e.g. keratin, chromgranin A, synaptophysin, and neurofilaments).
Clone
ENO2/1462
Isotype
IgG2b
Host species
Mouse
Species Reactivity
Human
Cellular Localization
Cytoplasm
Positive Control
Neuroendocrine tumor
Applications
IHC
Intended Use
Research Use Only