IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
Clone
Polyclonal
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human, mouse, rat
Cellular Localization
nucleus
Positive Control
testis, cervical and rectum cancer
Applications
IHC, ICC/IF, WB
Intended Use
Research Use Only