IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
Clone
Polyclonal
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human, mouse, rat
Cellular Localization
nucleus
Positive Control
spleen, prostate, lung ca
Applications
ELISA, IF, IHC, WB
Intended Use
Research Use Only