IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. It plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. It is involved in host defense, acute phase reactions, immune responses, and hematopoiesis.
Clone
MD236
Isotype
IgG1k
Host species
Mouse
Species Reactivity
Human
Cellular Localization
Cytoplasm, extracellular (secreted)
Positive Control
Heart
Applications
IHC
Intended Use
Research Use Only
![IL-6 [MD236] (Hybridoma Growth Factor)](https://medaysis.com/wp-content/uploads/2023/01/IL-6-MD236-MC0472_human-adrenal-gland-e1697073680771.jpg)