HSV I & II (Herpes Simplex Virus I & II) [MD361R]

Herpes Simplex virus (HSV) is a double stranded DNA virus of which there are 2 types, HSV I and HSV II. HSV I and HSV II are extremely difficult to distinguish from each other. These viruses have a DNA genome, an icosahedral protein coat and are encased in a lipid membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. HSV1 usually establishes latency in the trigeminal ganglion, a collection of nerve cells near the ear. From the trigeminal ganglion, it tends to recur on the lower lip or face causing cold sores. HSV2 usually resides in the sacral ganglion at the base of the spine. From there, it recurs in the genital area. This antibody detects HSV I & II specific antigens in human cellular and tissue materials obtained from superficial lesions or biopsies and for the early identification of HSV in infected tissue.