The HIF-1 Alpha subunit of hypoxia-inducible factor 1 is a transcription factor that functions as a master transcriptional regulator of the adaptive response to hypoxia. HIF-1 activates the transcription of many genes, thus playing a role in various biological processes, including cardiovascular development, angiogenesis, energy metabolism, and cell survival.
Clone
H1α67
Isotype
IgG2b
Host species
Mouse
Species Reactivity
Human, mouse
Cellular Localization
nucleus, cytoplasm
Positive Control
breast carcinoma
Applications
ELISA, IHC, WB
Intended Use
Research Use Only