Belongs to the fascin family. Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Belongs to the fascin family. Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Clone
FSCN/417
Isotype
IgG2a/k
Host species
Mouse
Species Reactivity
Human
Cellular Localization
cytoplasm
Positive Control
tonsil, Hodgkin’s lymphoma
Applications
Flow Cyt., ICC/IF, IHC, WB
Intended Use
Research Use Only