Factor VIII Polyclonal

This antibody reacts with human von Willebrand factor, a large, multimeric protein synthesized by endothelial cells and stored in the Weibel-Palade granules. Studies have shown this antibody reacts specifically with the endothelial cells of normal, reactive, and neoplastic blood and lymphatic vessels, exhibiting a finely granular cytoplasmic staining. It also reacts with endocardium, platelets, and megakaryocytes.