Cytokeratin 19 [BA17]

$269.00$520.00

SKU: N/A Category:

Cytokeratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in non-keratinizing stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes. CK19 antibody is a useful tool for the identification of epithelial tumors. It is helpful in distinguishing hepatocellular carcinoma (CK19-) from cholangiocarcinoma (CK19+) or metastatic carcinoma in liver (CK19+).

Clone
BA17

Isotype
IgG1k

Host species
Mouse

Species Reactivity
Human, mouse

Cellular Localization
cytoplasm

Positive Control
colon, colon ca

Applications
Flow Cyt., ICC/IF, IHC

Intended Use
Research Use Only

Download Datasheet