Collagen IV Alpha 5/COL4A5 Polyclonal

Human Collagen IV Alpha 5 is encoded by the COL4A5 gene. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.