Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neurosecretory granules of neuroendocrine cells. Chromogranin A showed broad expression in endocrine tissues including pituitary, adrenal medulla, thyroid, pancreatic islets and gastrointestinal tract. Chromogranin A represents the single most specific marker of neuroendocrine differentiation in general use. It is useful for identification of neuroendocrine tumors.
Clone
LK2H10
Isotype
IgG1k
Host species
Mouse
Species Reactivity
Human, monkey, pig, mouse, rat. Does not react with guinea pig, sheep & rabbit
Cellular Localization
cytoplasm
Positive Control
pancreas, neuroendocrine tumor
Applications
IHC
Intended Use
Research Use Only