Chromogranin A [LK2H10]

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Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neurosecretory granules of neuroendocrine cells. Chromogranin A showed broad expression in endocrine tissues including pituitary, adrenal medulla, thyroid, pancreatic islets and gastrointestinal tract. Chromogranin A represents the single most specific marker of neuroendocrine differentiation in general use. It is useful for identification of neuroendocrine tumors.

Clone
LK2H10

Isotype
IgG1k

Host species
Mouse

Species Reactivity
Human, monkey, pig, mouse, rat. Does not react with guinea pig, sheep & rabbit

Cellular Localization
cytoplasm

Positive Control
pancreas, neuroendocrine tumor

Applications
IHC

Intended Use
Research Use Only

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