CD147/EMMPRIN/Neurothelin [8D6]

$269.00$520.00

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This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Clone
8D6

Isotype
IgG1k

Host species
Mouse

Species Reactivity
Human

Cellular Localization
membrane

Positive Control
colon ca, placenta

Applications
Flow Cyt, ICC/IF, IHC

Intended Use
Research Use Only

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