CD117/c-Kit [EPR22566-344]

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Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor. This anti-CD117 has been validated with excellent staining result by NordiQC, an independent scientific organization, promoting the quality of immunohistochemistry for pathology laboratories.

Clone
EPR22566-344

Isotype
IgG

Host species
Rabbit

Species Reactivity
Human, mouse, rat

Cellular Localization
Membrane, cytoplasm

Positive Control
Lung adenocarcinoma

Applications
IHC, WB

Intended Use
Research Use Only

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