CA125/MUC16 (Ovarian Tumor Marker) [OCA125/2349R]

Carcinoma antigen 125 (CA125) is a high molecular weight tumor antigen. It is a heavily glycosylated mucin encoded by MUC16 gene. It is expressed on ovarian carcinoma and several epithelial tumors including endometrial carcinoma, cervix carcinoma and clear cell carcinoma of bladder. In addition, CA125 also binds to mesothelin and expressed on mesothelioma. The binding of CA125 to mesothelin may contribute to ovarian cancer metastasize to peritoneum.