It recognizes a protein of 54kDa, which is identified antitrypsin (AAT). The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
Clone
AAT/1378
Isotype
IgG1
Host species
Mouse
Species Reactivity
Human
Cellular Localization
cytoplasm
Positive Control
Tonsil, Hepatocellular Carcinoma or Histiocytoma, HepG2 Cells
Applications
Flow Cyt., IF, IHC, WB
Intended Use
Research Use Only