Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Clone
E11
Isotype
IgG1k
Host species
Mouse
Species Reactivity
Human, mouse, rat
Cellular Localization
Membrane
Positive Control
Kidney, testis
Applications
ELISA, IF, IHC, IP, WB
Intended Use
Research Use Only