CD163 [MD171R]

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CD163 is an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, thereby protecting tissues from free hemoglobin-mediated oxidative damage. Expression of CD163 is restricted to cells of the monocyte/macrophage lineage. This antibody labels monocytes and macrophages in the spleen and peripheral blood. The CD163 antibody might be used for identifying tumors of monocytic origin.

Clone
MD171R

Isotype
IgG

Host species
Rabbit

Species Reactivity
Human

Cellular Localization
Membrane, cytoplasm

Positive Control
Spleen, uterus

Applications
ELISA, IHC

Intended Use
Research Use Only

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