CD1a [O10]

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Cluster of Differentiation 1a (CD1a) is part of a family of major histocompatibility complex (MHC) antigen-like glycoproteins that associate with beta-2-microglobulin. CD1a binds self and non-self lipid and glycolipid antigens, presenting them to T-cell receptors on natural killer T-cells. CD1a antibody labels cortical thymocytes, Langerhans’ cells and dendritic cells. It has been used to identify Langerhans’ cell histiocytosis and precursor T lymphoblastic lymphoma/leukemia.

Clone
O10

Isotype
IgG1k

Host species
Mouse

Species Reactivity
Human

Cellular Localization
membrane

Positive Control
thymus, tonsil

Applications
Flow Cyt., IF, IHC, WB

Intended Use
Research Use Only

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