CD21 is a single-pass type 2 transmembrane protein that serves as the complement receptor for C3d and the Epstein-Barr virus. CD21 labels follicular dendritic cells and mature B cells particularly in marginal and mantle zone of lymphoid tissues. It is a useful marker to identify neoplasms derived from follicular dendritic cells.
Clone
CR2/3124R
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human
Cellular Localization
membrane
Positive Control
tonsil, lymphoma
Applications
IHC, Flow Cyt., IF, WB
Intended Use
Research Use Only