Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722, resulting in stimulatation of its RhoA binding activity.
Catalog No. RC0022
Clone
Polyclonal
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human, mouse, rat
Cellular Localization
cytoplasm
Positive Control
breast carcinoma
Applications
IF, IHC, WB
Intended Use
Research Use Only