RBM24 Polyclonal

RNA-binding proteins have a pivotal role in post-transcriptionally regulating gene expression. During early development they exhibit temporally and spatially regulated expression pattern, and affect the proteome of a single cell by controlling alternative splicing, transport, localization, and stability of their target RNAs. Their expression is tissue-specific, and their crucial influence on the protein set-up, especially in muscle cells, has become recognized recently. RBM24 is one RNA-binding protein and plays a fundamental role in regulating cardiac gene expression, sarcomeric assembly, and cardiac contractility and may thus represent a novel pathway to cardiomyopathy. RBM24 Plays a role in myogenic differentiation by regulating MYOG levels. Binds to the 3′-UTR of MYOG mRNA and regulates its stability. 2 isoforms of the human protein are produced by alternative splicing.