Proliferating cell nuclear antigen (PCNA) is a DNA polymerase accessory factor that is required for DNA replication during S phase of the cell cycle and for resynthesis during nucleotide excision repair of damaged DNA. The PCNA antibody detects proliferating cells in both normal and tumor cells. Anti-PCNA labeling index has been shown to be associated with tumor prognosis.
Clone
PC10
Isotype
IgG2a/k
Host species
Mouse
Species Reactivity
Human, monkey, pig, mouse, rat, chicken, zebrafish, Drosophila melanogaster, yeast
Cellular Localization
nucleus
Positive Control
tonsil
Applications
Flow Cyt., IF, IHC, WB
Intended Use
Research Use Only