Parvovirus B19 [R92F6]

Parvovirus B19 is a small DNA virus which causes erythema infectiosum (fifth disease) or “slapped cheek syndrome” in children. PARVO replicates in bone marrow cells and inhibits red blood cell (RBC) production (erythropoiesis) causing hemolytic complications. It has been implicated in hydrops fetalis which causes spontaneous abortion in humans and causes chronic anemia in individuals with human immunodeficiency virus (HIV) and can infect sickle cell patients with erythrocyte (red blood cell) abnormalities. Clone R92F6 targets the capsid proteins VP1 (84 kD) and VP2 (58 kD) of human Parvovirus.