NSE is specifically detected in neurons and neurodendocrine cells, and their corresponding tumors. Anti-NSE antibody is a useful marker for identification of peripheral nerves, neural and neuroendocrine tumors, such as neuroblastomas, retinoblastomas, desmoplastic melanoma, and small cell lung carcinoma when used with a panel of antibodies (e.g. keratin, chromgranin A, synaptophysin, and neurofilaments).
Clone
5E2
Isotype
IgG2a
Host species
Mouse
Species Reactivity
Human
Cellular Localization
Cytoplasm
Positive Control
Neuroendocrine tumor
Applications
IHC, WB
Intended Use
Research Use Only