MUC2 [CCP58]

Mucins are high molecular weight glycoproteins produced by many epithelial tissues. MUC2 is a member of the mucin protein family. MUC2 is secreted and forms an insoluble mucous barrier that protects the gut lumen. MUC2 is the major secretory glycoprotein specifically expressed in goblet cells of the intestinal and airway epithelium. Its expression is a common feature of all mucinous carcinomas derived from different organs including breast, stomach, colon and prostate where it may act as a potential prognostic indicator.