HLA-DRA (MHC II) [19-26.1 same as MB-26.1]

Human class II major histocompatibility complex (MHC) products are essential initiators of cellular immune responses. There are three major isotypes of human class II MHC molecules; HLA-DR, HLA-DP, and HLA-DQ, each of which consists of an alpha and beta chain. HLA-DR alpha is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune response. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular proteins to T cells.
Human class II major histocompatibility complex (MHC) products are essential initiators of cellular immune responses. There are three major isotypes of human class II MHC molecules; HLA-DR, HLA-DP, and HLA-DQ, each of which consists of an alpha and beta chain. HLA-DR alpha is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in the immune response. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage; these class II molecules present peptides derived from extracellular proteins to T cells.