Cytokeratin LMW [KRTL/1077]

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Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20.This antibody recognizes low molecular weight cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19(40) of the acidic family.

Clone
KRTL/1077

Isotype
IgG1k

Host species
Mouse

Species Reactivity
Human, rat

Cellular Localization
cytoplasm

Positive Control
colon, colon ca

Applications
Flow Cyt.(0.5-1ug/million cells), ICC/IF (1-2ug/ml), IHC, WB (0.5-1ug/ml)

Intended Use
Research Use Only

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