Each epithelium contains at least one acidic and one basic keratin. Anti-Cytokeratin clone AE1 labels most acidic keratins and stains most epithelia and their neoplasms. The antibody is suited to distinguish poorly differentiated carcinomas from non-epithelial neoplasms.
Clone
AE1
Isotype
IgG1k
Host species
Mouse
Species Reactivity
Human, monkey, cow, dog, rabbit, mouse, rat, chicken, turtle
Cellular Localization
cytoplasm
Positive Control
tissue with epithelial cells (e.g. Cervix, GI track, skin, tonsil)
Applications
Flow Cyt., IF, IHC, WB
Intended Use
Research Use Only