This antibody has a primary reactivity with human keratin proteins that correspond to Moll`s peptides no.7 and 8, 48 kDa and 52 kDa, respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on stratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) may not react with some squamous cell carcinomas.
Clone
CAM5.2
Isotype
IgG2a/κ
Host species
Mouse
Species Reactivity
Human
Cellular Localization
cytoplasm
Positive Control
ovarian ca
Applications
IHC
Intended Use
Research Use Only