CD99 is a transmembrane glycoprotein, also known as MIC2. It is involved in T cell adhesion, leukocyte migration and differentiation of primitive neuroectodermal cell. CD99 labels lymphocyte, ovarian granulosa cells, pancreatic islet cells, sertoli cells, CNS ependymal cells and endothelial cells. CD99 has been useful in diagnosis of Ewing’s sarcoma, sex cord-stromal tumor, endocrine tumor of pancreas. Additionally, it is found in a subset of other tumors including lymphoblastic lymphoma, breast carcinoma and other malignancies.
Clone
MD225R
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human
Cellular Localization
membrane
Positive Control
Tonsil, pancreas, uterus, Ewing s sarcoma
Applications
IHC
Intended Use
Research Use Only