“Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation, in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesothe liomas and some pulmonary adenocarcinomas.”
Clone
CALB2/2685
Isotype
IgG1k
Host species
Mouse
Species Reactivity
Human
Cellular Localization
Cytoplasm, nucleus
Positive Control
Mesothelioma
Applications
IHC
Intended Use
Research Use Only