Glucagon is synthesized and released by the alpha-cells of the islets of Langerhans in pancreas. It regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis, stimulates fluid secretions from the intestine and suppresses the release of gastrin. Anti-glucagon is useful in identification of glucagonoma
Clone
MD282R
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human
Cellular Localization
cytoplasm, some nucleus
Positive Control
pancreas, glucagonoma
Applications
IHC
Intended Use
Research Use Only