This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock (HSP70) proteins. This gene is a member of the type 2 subgroup of DNAJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis. Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins.
Clone
Polyclonal
Isotype
IgG
Host species
Rabbit
Species Reactivity
Human
Cellular Localization
cytoplasm
Positive Control
kidney, testis, placenta
Applications
IHC, ELISA
Intended Use
Research Use Only